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Monday, August 18, 2014

Ebola Emergency ZMAPP Production Rates & Costs



Based NIH data, the POTRBLOG team has been able to calculate that Kentucky Bioprocessing has the Rough Order of Magnitude [ROM] emergency capability to produce 97,751 courses of Ebola treatment per month. The lead time to meet this emergency production rate is approximately 5 weeks.



One very concerning bit of information, the ZMAPP treatment has components which are reported to produce one escaped mutant per every twenty non-human primates treated. And, that the escaped mutants do exhibit reversion.


Source and cost data to follow:

Filovirus Medical Countermeasures (MCM) Workshop

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2 comments:

  1. You posted, "One very concerning bit of information, the ZMAPP treatment has components which are reported to produce one escaped mutant per every twenty non-human primates treated. And, that the escaped mutants do exhibit reversion."

    Can you provide a link to the study/studies which document this?

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    Replies
    1. The information came from the presentation at the 2013 Filovirus conference (linked in the sources above)
      I believe he was referencing this study:
      http://stm.sciencemag.org/content/4/138/138ra81.full

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